中文名稱: DSG2抗原(重組蛋白)
英文名稱: DSG2 Antigen (Recombinant Protein)
別 名: HDGC; CDHF5; ARVC10; ARVD10; CMD1BB
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from C terminal 300 amino acids of human DSG2 |
Full name: |
desmoglein 2 |
Synonyms: |
HDGC; CDHF5; ARVC10; ARVD10; CMD1BB |
Swissprot: |
Q14126 |
Gene Accession: |
BC099655 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. |