中文名稱:DIRAS3抗原(重組蛋白)
英文名稱: DIRAS3 Antigen (Recombinant Protein)
別 名: ARHI; NOEY2
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 1-226 amino acids of human DIRAS3
技術規格:
Full name:
DIRAS family, GTP-binding RAS-like 3
Synonyms:
ARHI; NOEY2
Swissprot:
O95661
Gene Accession:
BC005362
Purity:
>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:
Escherichia coli
Tags:
His tag C-Terminus, GST tag N-Terminus
Background:
This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.