Name: PIK3R1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱(chēng)：PIK3R1抗原（重組蛋白）

英文名稱(chēng)： PIK3R1 Antigen (Recombinant Protein)

別名： p85, GRB1, p85-ALPHA

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概述

Fusion protein corresponding to a region derived from 113-301 amino acids of human PIK3R1

技術(shù)規(guī)格

Full name:	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Synonyms:	p85, GRB1, p85-ALPHA
Swissprot:	P27986
Gene Accession:	BC030815
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.

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