Name: PAK6抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： PAK6抗原（重組蛋白）

英文名稱： PAK6 Antigen (Recombinant Protein)

別名： PAK5

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to a region derived from 407-658 amino acids of human PAK6

技術規格

Full name:	p21 protein (Cdc42/Rac)-activated kinase 6
Synonyms:	PAK5
Swissprot:	Q9NQU5
Gene Accession:	BC035596
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.

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