Name: OAS2抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： OAS2抗原（重組蛋白）

英文名稱： OAS2 Antigen (Recombinant Protein)

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to a region derived from 11-335 amino acids of human OAS2

技術規格

Full name:	2'-5'-oligoadenylate synthetase 2, 69/71kDa
Swissprot:	P29728
Gene Accession:	BC049215
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

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