中文名稱: CD160抗原(重組蛋白)
英文名稱: CD160 Antigen (Recombinant Protein)
別 名: NK1; BY55; NK28
儲 存:冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 27-159 amino acids of human CD160 |
Full name: |
CD160 molecule |
Synonyms: |
NK1; BY55; NK28 |
Swissprot: |
O95971 |
Gene Accession: |
BC014465 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. |