Background: |
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
TSC2 |
Immunogen: |
Synthetic peptide of humanTSC2 |
Full name: |
tuberous sclerosis 2 |
Synonyms: |
LAM; TSC4; PPP1R160 |
SwissProt: |
P49815 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human esophagus cancer |
IHC Recommend dilution: |
10-50 |
WB Predicted band size: |
201 kDa |
WB Positive control: |
A172 cells |
WB Recommended dilution: |
200-1000 |