中文名稱:ASH2L抗原(重組蛋白)
英文名稱: ASH2L Antigen (Recombinant Protein)
別 名: ASH2; Bre2; ASH2L1; ASH2L2
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 360-583 amino acids of human ASH2L |
技術規(guī)格:
Full name: |
ASH2 like, histone lysine methyltransferase complex subunit |
Synonyms: |
ASH2; Bre2; ASH2L1; ASH2L2 |
Swissprot: |
Q9UBL3 |
Gene Accession: |
BC015936 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis. |