Name: ASB8抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：ASB8抗原（重組蛋白）

英文名稱： ASB8 Antigen (Recombinant Protein)

別名： PP14212

儲存： 冷凍（-20℃）

相關類別： 抗原

概述：

Fusion protein corresponding to a region derived from 9-179 amino acids of human ASB8

技術規格：

Full name:	ankyrin repeat and SOCS box containing 8
Synonyms:	PP14212
Swissprot:	Q9H765
Gene Accession:	BC001321
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas.

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