Name: ASB2抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：ASB2抗原（重組蛋白）

英文名稱： ASB2 Antigen (Recombinant Protein)

別名： ASB-2

儲存： 冷凍（-20℃）

相關類別：抗原

概述：

Fusion protein corresponding to a region derived from 340-535 amino acids of human ASB2

技術規格：

Full name:	ankyrin repeat and SOCS box containing 2
Synonyms:	ASB-2
Swissprot:	Q96Q27
Gene Accession:	BC032354
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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