Name: GRAP抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： GRAP抗原（重組蛋白）

英文名稱： GRAP Antigen (Recombinant Protein)

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Full length fusion protein

技術規格

Full name:	GRB2-related adaptor protein
Swissprot:	Q13588
Gene Accession:	BC035856
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

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