Full name: |
dicarbonyl/L-xylulose reductase |
Synonyms: |
XR; DCR; HCR2; P34H; HCRII; KIDCR; PNTSU; SDR20C1 |
Swissprot: |
Q7Z4W1 |
Gene Accession: |
BC001470 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene. |