英文名稱: CRADD Antigen (Recombinant Protein)
別 名: MRT34; RAIDD
儲 存: 冷凍(-20
概 述
Full name: |
CASP2 and RIPK1 domain containing adaptor with death domain |
Synonyms: |
MRT34; RAIDD |
Swissprot: |
P78560 |
Gene Accession: |
BC037905 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. |