別 名: cytochrome c oxidase subunit VIIIA (ubiquitous); COX, COX8, VIII, COX8L, COX8-2, VIII-L
概 述
Full name: |
cytochrome c oxidase subunit VIIIA (ubiquitous) |
Synonyms: |
COX, COX8, VIII, COX8L, COX8-2, VIII-L |
Swissprot: |
P10176 |
Gene Accession: |
BC063025 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. |