中文名稱: CHMP3抗原(重組蛋白)
英文名稱: CHMP3 Antigen (Recombinant Protein)
別 名: NEDF; VPS24; CGI-149
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述
Full name: |
charged multivesicular body protein 3 |
Synonyms: |
NEDF; VPS24; CGI-149 |
Swissprot: |
Q9Y3E7 |
Gene Accession: |
BC004419 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. |