中文名稱: CHST11 抗原(重組蛋白)
英文名稱: CHST11 Antigen (Recombinant Protein)
別 名: carbohydrate sulfotransferase 11; C4ST; C4ST1; C4ST-1; HSA269537
概 述
Full name: |
carbohydrate sulfotransferase 11 |
Synonyms: |
C4ST; C4ST1; C4ST-1; HSA269537 |
Swissprot: |
Q9NPF2 |
Gene Accession: |
BC013315 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |