中文名稱: CBY1抗原(重組蛋白)
英文名稱: CBY1 Antigen (Recombinant Protein)
別 名: CBY; arb1; PGEA1; C22orf2; Chibby1; PIGEA14; PIGEA-14; HS508I15A
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
Full name: |
chibby family member 1, beta catenin antagonist |
Synonyms: |
CBY; arb1; PGEA1; C22orf2; Chibby1; PIGEA14; PIGEA-14; HS508I15A |
Swissprot: |
Q9Y3M2 |
Gene Accession: |
BC016139 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. |