中文名稱:兔抗AKT1(Ab-326) 多克隆抗體
英文名稱: Anti-AKT1(Ab-326) rabbit polyclonal antibody
別 名: AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA
儲 存: 冷凍(-20℃) 避光
宿 主: Rabbit
抗 原: AKT1(Ab-326)
反應種屬: Human Mouse
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術規格
Background: |
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. |
Applications: |
WB, IHC, IF |
Name of antibody: |
AKT1(Ab-326) |
Immunogen: |
Synthesized non-phosphopeptide derived from human Akt around the phosphorylation site of tyrosine 326 (N-D-Y(p)-G-R). |
Full name: |
v-akt murine thymoma viral oncogene homolog 1 |
Synonyms: |
AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA |
SwissProt: |
P31749 |
IHC positive control: |
Human breast carcinoma tissue |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
56 kDa |
WB Positive control: |
NIH/3T3 cells treated with Insulin (0.01U/ml, 15mins) lysate |
WB Recommended dilution: |
500-3000 |
IF positive control: |
Hela cells |
IF Recommend dilution: |
100-500 |