中文名稱: ACTC1抗原(重組蛋白)
Fusion protein corresponding to a region derived from 178-377 amino acids of human ACTC1
技術規格
Full name: |
actin, alpha, cardiac muscle 1 |
Synonyms: |
ACTC; ASD5; CMD1R; CMH11; LVNC4 |
Swissprot: |
P68032 |
Gene Accession: |
BC009978 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). |