Full name: |
ankyrin repeat domain 1 (cardiac muscle) |
Synonyms: |
ALRP; CARP; C-193; CVARP; MCARP; bA320F15.2 |
Swissprot: |
Q15327 |
Gene Accession: |
BC018667 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system. |