中文名稱:APPBP2抗原(重組蛋白)
英文名稱: APPBP2 Antigen (Recombinant Protein)
別 名: PAT1; APP-BP2; HS.84084
儲 存: 冷凍(-20℃)
相關(guān)類別 :抗原
概 述:
Fusion protein corresponding to a region derived from 322-585 amino acids of human APPBP2 |
Full name: |
amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
Synonyms: |
PAT1; APP-BP2; HS.84084 |
Swissprot: |
Q92624 |
Gene Accession: |
BC018121 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. |