購物車
幫助
021-54845833/15800441009
中文名稱：APLF 抗原（重組蛋白）
英文名稱： APLF Antigen (Recombinant Protein)
別 名： aprataxin and PNKP like factor; APFL; PALF; Xip1; C2orf13
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human APLF |
|
Full name: |
aprataxin and PNKP like factor |
|
Synonyms: |
APFL; PALF; Xip1; C2orf13 |
|
Swissprot: |
Q8IW19 |
|
Gene Accession: |
BC041144 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. |
