中文名稱:ALDH1L1 抗原(重組蛋白)
英文名稱: ALDH1L1 Antigen (Recombinant Protein)
別 名: aldehyde dehydrogenase 1 family member L1; FDH; FTHFD; 10-fTHF; 10-FTHFDH
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 256-505 amino acids of human ALDH1L1 |
Full name: |
aldehyde dehydrogenase 1 family member L1 |
Synonyms: |
FDH; FTHFD; 10-fTHF; 10-FTHFDH |
Swissprot: |
O75891 |
Gene Accession: |
BC027241 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. |