中文名稱:ADAM10 抗原(重組蛋白)
英文名稱: ADAM10 Antigen (Recombinant Protein)
別 名: ADAM metallopeptidase domain 10; kuz; AD10; MADM; CD156c; HsT18717
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to C terminal 209 amino acids of human ADAM10 |
Full name: |
ADAM metallopeptidase domain 10 |
Synonyms: |
kuz; AD10; MADM; CD156c; HsT18717 |
Swissprot: |
O14672 |
Gene Accession: |
BC126253 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. Sheddase, a generic name for the ADAM metallopeptidase, functions primarily to cleave membrane proteins at the cellular surface. Once cleaved, the sheddases release soluble ectodomains with an altered location and function. |