中文名稱:ACTR1A 抗原(重組蛋白)
英文名稱: ACTR1A Antigen (Recombinant Protein)
別 名: actin related protein 1A; ARP1; Arp1A; CTRN1
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 127-376 amino acids of human ACTR1A |
Full name: |
actin related protein 1A |
Synonyms: |
ARP1; Arp1A; CTRN1 |
Swissprot: |
P61163 |
Gene Accession: |
BC000693 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. |