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  • ACTL7B 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW15732
    • 應用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現貨
    • 商品庫存:90
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中文名稱:ACTL7B 抗原(重組蛋白)

英文名稱: ACTL7B Antigen (Recombinant Protein)

別      名: actin-like 7B; Tact1

儲      存: 冷凍(-20℃)

相關類別: 抗原


概  述:

Fusion protein corresponding to C terminal 250 amino acids of human ACTL7B


技術規格:

Full name:

actin-like 7B

Synonyms:

Tact1

Swissprot:

Q9Y614

Gene Accession:

BC033789

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia.



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