中文名稱:ACSL4抗原(重組蛋白)
英文名稱: ACSL4 Antigen (Recombinant Protein)
別 名: ACS4; FACL4; LACS4; MRX63; MRX68
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human ACSL4 |
Full name: |
acyl-CoA synthetase long-chain family member 4 |
Synonyms: |
ACS4; FACL4; LACS4; MRX63; MRX68 |
Swissprot: |
O60488 |
Gene Accession: |
BC034959 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants. |