中文名稱:ACOX1 抗原(重組蛋白)
英文名稱: ACOX1 Antigen (Recombinant Protein)
別 名: Acyl-CoA oxidase 1, palmitoyl; ACOX; SCOX; PALMCOX
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human ACOX1 |
Full name: |
Acyl-CoA oxidase 1, palmitoyl |
Synonyms: |
ACOX; SCOX; PALMCOX |
Swissprot: |
Q15067 |
Gene Accession: |
BC010425 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified. |