中文名稱:ACE2 抗原(重組蛋白)
英文名稱: ACE2 Antigen (Recombinant Protein)
別 名: angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; ACEH
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 556-740 amino acids of human ACE2 |
Full name: |
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
Synonyms: |
ACEH |
Swissprot: |
Q9BYF1 |
Gene Accession: |
BC039902 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63 |