Background: |
Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]). |
Applications: |
ELISA, IHC |
Name of antibody: |
CNST |
Immunogen: |
Fusion protein of human CNST |
Full name: |
consortin, connexin sorting protein |
Synonyms: |
C1orf71; PPP1R64 |
SwissProt: |
Q6PJW8 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human cervical cancer and Human brain |
IHC Recommend dilution: |
50-200 |