Background: |
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. [provided by RefSeq, Jul 2008] |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
GDI1 |
Immunogen: |
Fusion protein of human GDI1 |
Full name: |
Rab GDP dissociation inhibitor alpha |
Synonyms: |
FLJ41411, GDIL, MRX41, MRX48, OPHN2, RABGDIA, XAP-4 |
SwissProt: |
P31150 |
ELISA Recommended dilution: |
500-1000 |
IHC positive control: |
Human brain and Human tonsil |
IHC Recommend dilution: |
25-50 |
WB Predicted band size: |
51 kDa |
WB Positive control: |
Human fetal brain tissue |
WB Recommended dilution: |
200-1000 |