Background: |
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). |
Applications: |
ELISA, IHC |
Name of antibody: |
GCKR |
Immunogen: |
Synthetic peptide of human GCKR |
Full name: |
glucokinase (hexokinase 4) regulator |
Synonyms: |
GKRP; FGQTL5 |
SwissProt: |
Q14397 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human colon cancer and Human gastric cancer |
IHC Recommend dilution: |
100-300 |
WB Predicted band size: |
69 kDa |
WB Positive control: |
Mouse liver tissue |
WB Recommended dilution: |
500-2000 |