技術規格
Background: |
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. |
Applications: |
WB |
Name of antibody: |
PMS1 |
Immunogen: |
Fusion protein of human PMS1 |
Full name: |
PMS1 homolog 1, mismatch repair system component |
Synonyms: |
MLH2; PMSL1; hPMS1; HNPCC3 |
SwissProt: |
P54277 |
WB Predicted band size: |
106 KD |
WB Positive control: |
Hela, Jurkat, HepG2 cell lysates |
WB Recommended dilution: |
200-1000 |