Background: |
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. |
Applications: |
WB |
Name of antibody: |
STC1 |
Immunogen: |
Fusion protein of human STC1 |
Full name: |
stanniocalcin 1 |
Synonyms: |
STC |
SwissProt: |
P52823 |
WB Predicted band size: |
28 KD |
WB Positive control: |
MDCK cell lysate |
WB Recommended dilution: |
500-2000 |