Background: |
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq]. |
Applications: |
WB |
Name of antibody: |
SNAI2 |
Immunogen: |
Fusion protein of human SNAI2 |
Full name: |
snail family zinc finger 2 (SNAI2) |
Synonyms: |
SLUG; SLUGH1; SNAIL2; WS2D |
SwissProt: |
O43623 |
WB Predicted band size: |
30 kDa |
WB Positive control: |
MCF-7 cell lysate |
WB Recommended dilution: |
200-1000 |