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    • 品牌 : 通蔚生物
    • 目錄號 : TW11915
    • 應用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現貨
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中文名稱: 小鼠抗RPL7A單克隆抗體

英文名稱: Anti-RPL7A mouse monoclonal antibody

別     名: ribosomal protein L7a; L7A; TRUP; SURF3

相關類別: 一抗

儲     存: 冷凍(-20℃)

宿     主: Mouse

抗     原: RPL7A

反應種屬: Human, Mouse

標 記 物: Unconjugate

克隆類型: mouse monoclonal

技術規格

Background:

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Applications:

WB, IHC, IF

Name of antibody:

RPL7A

Immunogen:

Fusion protein of human RPL7A

Full name:

ribosomal protein L7a

Synonyms:

L7A; TRUP; SURF3

SwissProt:

P62424

IHC positive control:

Human tonsil tissue and Human gastric tissue

IHC Recommend dilution:

200-500

WB Predicted band size:

30 KD

WB Positive control:

A431, Raji, Hela, MCF7, 293T, RAW264.7, NIH/3T3 cell lysates

WB Recommended dilution:

500-2000

IF Positive control:

NIH/3T3 cells

IF Recommended dilution:

50-100



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