別 名: ring finger protein 14; ARA54; HFB30; TRIAD2; HRIHFB2038
技術規格
Background: |
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. |
Applications: |
WB, IHC |
Name of antibody: |
RNF14 |
Immunogen: |
Fusion protein of human RNF14 |
Full name: |
ring finger protein 14 |
Synonyms: |
ARA54; HFB30; TRIAD2; HRIHFB2038 |
SwissProt: |
Q9UBS8 |
IHC positive control: |
Human colorectal cancer and Human kidney tissue |
IHC Recommend dilution: |
200-500 |
WB Predicted band size: |
54 KD |
WB Positive control: |
Jurkat, Hela, RAW264.7 cell lysates |
WB Recommended dilution: |
200-1000 |