Background: |
The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Applications: |
WB, IHC |
Name of antibody: |
RLIM |
Immunogen: |
Fusion protein of human RLIM |
Full name: |
ring finger protein, LIM domain interacting |
Synonyms: |
MRX61; RNF12; NY-REN-43 |
SwissProt: |
Q9NVW2 |
IHC positive control: |
Human liver tissue |
IHC Recommend dilution: |
200-500 |
WB Predicted band size: |
69 KD |
WB Positive control: |
HepG2, Hela, A549 cell lysates |
WB Recommended dilution: |
500-2000 |