Background: |
This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. |
Applications: |
WB, IHC, IF |
Name of antibody: |
RAB21 |
Immunogen: |
Fusion protein of human RAB21 |
Full name: |
RAB21, member RAS oncogene family (RAB21) |
Synonyms: |
KIAA0118 |
SwissProt: |
Q9UL25 |
IHC positive control: |
human prostate tissue |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
24 kDa |
WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates |
WB Recommended dilution: |
500-2000 |