Background: |
MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival |
Applications: |
ELISA, IHC |
Name of antibody: |
MACC1 |
Immunogen: |
Synthetic peptide of human MACC1 |
Full name: |
metastasis associated in colon cancer 1 |
Synonyms: |
7A5; SH3BP4L |
SwissProt: |
Q6ZN28 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
25-100 |