Fusion protein corresponding to a region derived from 18-163 amino acids of human HINT2 |
技術規格
Full name: |
histidine triad nucleotide binding protein 2 |
Synonyms: |
HIT-17 |
Swissprot: |
Q9BX68 |
Gene Accession: |
BC047737 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Hint2 (histidine triad nucleotide binding protein 2), also known as HIT-17, is a 163 amino acid secreted protein that contains one HIT domain, a histidine triad that has catalytic activity toward the ?-phosphate of ribonucleotides. Via its HIT domain, Hint2 is thought to function as a hydrolase that is encoded by a gene which maps to chromosome 9. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia and Familial dysautonomia are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. |