相關類別: 一抗
Background: |
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. |
Applications: |
ELISA, IHC |
Name of antibody: |
LOXL4 |
Immunogen: |
Synthetic peptide of human LOXL4 |
Full name: |
lysyl oxidase-like 4 |
Synonyms: |
LOXC |
SwissProt: |
Q96JB6 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human esophagus cancer |
IHC Recommend dilution: |
25-100 |