購物車
幫助
021-54845833/15800441009
技術規格
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Background: |
The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
LMTK2 |
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Immunogen: |
Synthesized peptide derived from internal of human LMTK2. |
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Full name: |
lemur tyrosine kinase 2 |
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Synonyms： |
BREK; KPI2; LMR2; cprk; KPI-2; AATYK2; PPP1R100 |
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SwissProt: |
Q8IWU2 |
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IHC positive control: |
Human brain tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
165 kDa |
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WB Positive control: |
LOVO cells lysate |
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WB Recommended dilution: |
500-3000 |
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IF positive control: |
HepG2 cells |
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IF Recommend dilution: |
100-500 |
