Background: |
Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity). |
Applications: |
ELISA, IHC |
Name of antibody: |
LDB1 |
Immunogen: |
Fusion protein of human LDB1 |
Full name: |
LIM domain binding 1 |
Synonyms: |
NLI; CLIM2; LDB-1; CLIM-2 |
SwissProt: |
Q86U70 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human ovarian cancer and Human thyroid cancer |
IHC Recommend dilution: |
70-350 |