Background: |
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
LASP1 |
Immunogen: |
Full length fusion protein |
Full name: |
LIM and SH3 protein 1 |
Synonyms: |
MLN50; Lasp-1 |
SwissProt: |
Q14847 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human tonsil |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
30 kDa |
WB Positive control: |
Hela and 293T cell,Mouse brain tissue and Human kidney tissue lysates |
WB Recommended dilution: |
500-2000 |