購物車
幫助
021-54845833/15800441009
技術規(guī)格
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Background: |
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
KRT81 |
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Immunogen: |
Fusion protein of human KRT81 |
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Full name: |
keratin 81 |
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Synonyms: |
HB1; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1 |
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SwissProt: |
Q14533 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human colorectal cancer and Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
55 kDa |
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WB Positive control: |
Hela cell lysate |
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WB Recommended dilution: |
200-1000 |
