Background: |
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. |
Applications: |
WB |
Name of antibody: |
KRT8(Phospho-Ser432) |
Immunogen: |
Peptide sequence around phosphorylation site of Serine 432 (L-T-S(p)-P-G) derived from Human Keratin 8. |
Full name: |
keratin 8 |
Synonyms: |
K8; KO; CK8; CK-8; CYK8; K2C8; CARD2 |
SwissProt: |
P05787 |
WB Predicted band size: |
54 kDa |
WB Positive control: |
A549 cells lysates |
WB Recommended dilution: |
500-1000 |