技術規格
Background:
The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.
Applications:
ELISA, WB, IHC
Name of antibody:
KLF7
Immunogen:
Fusion protein of human KLF7
Full name:
Kruppel-like factor 7 (ubiquitous)
Synonyms:
UKLF
SwissProt:
O75840
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human thyroid cancer and human gastric cancer
IHC Recommend dilution:
50-200
WB Predicted band size:
33 kDa
WB Positive control:
Humna colon cancer and mouse kidney tissue, mouse testis and human fetal brain tissue
WB Recommended dilution:
500-2000