Fusion protein corresponding to a region derived from 30-406 amino acids of human ERP44 |
技術規格
Full name: |
endoplasmic reticulum protein 44 |
Synonyms: |
PDIA10; TXNDC4 |
Swissprot: |
Q9BS26 |
Gene Accession: |
BC005374 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum. |