中文名稱：ERBB3抗原（重組蛋白）

英文名稱：ERBB3 Antigen (Recombinant Protein)

儲存：冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to C terminal 250 amino acids of human ERBB3

技術規格

Full name:

erb-b2 receptor tyrosine kinase 3

Synonyms:

HER3, LCCS2, ErbB-3, c-erbB3, erbB3-S, MDA-BF-1, c-erbB-3, p180-ErbB3, p45-sErbB3, p85-sErbB3

Swissprot:

P21860

Gene Accession:

BC002706

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.

展開全部

ERBB3抗原（重組蛋白）說明書
下載

欧美一级免费-欧美一级免费观看-欧美一级免费看-欧美一级免费片-jizzjizz大全-jizzjizz国产精品

021-54845833/15800441009

ELISA試劑盒

PCR試劑盒

生化試劑盒

細胞系

細胞庫

基礎培養基

完全培養基

原代細胞

細胞專用培養基

菌株

生化試劑

病理染色液

科研抗體

標準品

血清

產品中心

最新產品

相關文章

ERBB3抗原（重組蛋白）

Full name:	erb-b2 receptor tyrosine kinase 3
Synonyms:	HER3, LCCS2, ErbB-3, c-erbB3, erbB3-S, MDA-BF-1, c-erbB-3, p180-ErbB3, p45-sErbB3, p85-sErbB3
Swissprot:	P21860
Gene Accession:	BC002706
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.